1965 Edmonton Eskimos
The Edmonton Eskimos ended the 1965 season with a record of five wins and 11 losses, missing the playoffs for a fourth straight season after finishing fifth in the CFL’s Western Conference. Jim Thomas ran for a team-best 981 yards and Tommy Joe Coffey had a career best in receiving yards with 1,286. Coffey would once again be named a CFL and West All-Star.
| 1965 (17th season) |
| Record: 5-11 (5th West) |
| Home: 3-5 | Away: 2-6 |
| Playoffs: Missed playoffs |
| Head coach: Neill Armstrong (2nd season) |
| CFL All-Stars: Tommy Joe Coffey |
| West All-Stars: Tommy Joe Coffey, E.A. Sims, Jim Thomas |
| Major award winners: None |
| Date | Opponent | Result (record) |
| July 30 | vs. Winnipeg Blue Bombers | L 21-14 (0-1) |
| August 7 | at BC Lions | L 13-38 (0-2) |
| August 13 | vs. Saskatchewan Roughriders | L 34-15 (0-3) |
| August 18 | at Calgary Stampeders | L 15-16 (0-4) |
| August 23 | vs. Calgary Stampeders | L 20-4 (0-5) |
| August 31 | vs. Toronto Argonauts | W 21-23 (1-5) |
| September 6 | at Saskatchewan Roughriders | W 24-22 (2-5) |
| September 11 | vs. Winnipeg Blue Bombers | W 25-30 (3-5) |
| September 20 | vs. Montreal Alouettes | L 24-13 (3-6) |
| September 25 | at Ottawa Rough Riders | L 1-40 (3-7) |
| September 28 | at Hamilton Tiger-Cats | W 9-3 (4-7) |
| October 2 | at BC Lions | L 27-41 (4-8) |
| October 9 | vs. BC Lions | W 12-14 (5-8) |
| October 16 | at Calgary Stampeders | L 19-28 (5-9) |
| October 23 | at Winnipeg Blue Bombers | L 24-40 (5-10) |
| October 30 | vs. Saskatchewan Roughriders | L 15-12 (5-11) |